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Gaskets used in pharmaceutical processing equipment have to do more than create a reliable seal. Depending on the application, they may be exposed to aggressive process media, repeated cleaning and sterilization cycles, elevated temperatures, pressure changes, and strict contamination-control requirements. This combination makes gasket selection particularly important. A material may offer excellent chemical resistance but perform poorly under repeated steam sterilization. Another may withstand the operating temperature but be unsuitable for product contact or the cleaning chemicals used between batches. Selecting the right gasket requires looking at the complete operating environment rather than any single material property. Understanding the factors...